Buffalo has won a bowl game for the first time.
Kyle Vantrease passed for a touchdown and ran for another and Buffalo topped Charlotte 31-9 in the Bahamas Bowl.
Jaret Patterson rushed for 173 yards and two touchdowns for the Bulls.
Victor Tucker caught a 51-yard catch-and-run touchdown pass from Chris Reynolds late in the third quarter for Charlotte.
The 49ers were in a bowl for the first time and saw their five-game winning streak snapped.
Charlotte finishes the season 7-6 under first-year head coach Will Healy. Seven wins is the school record for victories in one season.
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